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American Cruise Lines

American Cruise Lines

American Cruise Lines offers an exciting range of cruises across the USA including the Mississippi River, Alaska and New England. Their small ships and paddlewheelers carry up to just 190 guests. Enjoy attentive and personalised service on board, exquisite cuisine with regionally inspired dishes and daily entertainment including musicians, historians and naturalists joining every cruise.

Cruise Collection 2024/ 2025/ 2026

Finding Cruises
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  • Historic South & Golden Isles (Jacksonville to Charleston)

    American Cruise Lines
    Choice of Ships
    Charleston French Quarter South Carolina USA 7 Nights Cruise Only from £3567pp Jacksonville, Florida, Amelia Island, Florida, Jekyll Island, Georgia, Saint Simons Island, Georgia, Savannah, Georgia, Hilton Head Island, South Carolina, Beaufort, South Carolina, Charleston, South Carolina
  • Puget Sound & San Juan Islands

    American Cruise Lines
    Choice of Ships
    Seattle Skyline And Mount Rainier USA 7 Nights Cruise Only from £3693pp Seattle, Washington, Anacortes, Washington, San Juan Islands, Washington, Friday Harbor, Washington, Victoria, British Columbia, Port Angeles, Washington, Port Townsend, Washington, Poulsbo, Washington, Seattle, Washington
  • Maine Coast and Harbours

    American Cruise Lines
    Choice of Ships
    Bar Harbor lighthouse 7 Nights Cruise Only from £4051pp Portland (Maine), Bar Harbor, Castine - Belfast, Camden, Rockland, Boothbay Harbor, Bath, Portland
  • New England Islands

    American Cruise Lines
    American Star
    Martha's Vineyard 7 Nights Cruise Only from £4051pp Providence (Rhode Island), New Bedford (Massachusetts), Nantucket Island, Martha's Vineyard, Block Island, Newport, Bristol (Rhode Island), Providence
  • Yankee Seaports (Boston to New York)

    American Cruise Lines
    Choice of Ships
    New York Statue of Liberty 7 Nights Cruise Only from £4051pp New York, New York, Port Jefferson, New York, Sag Harbor, New York, Old Saybrook, Connecticut, New London, Connecticut, Newport, Rhode Island, Plymouth, Massachusetts, Boston, Massachusetts
  • Hudson River Fall Foliage

    American Cruise Lines
    Choice of Ships
    Troy Lock 7 Nights Cruise Only from £4535pp New York (USA), West Point, Kingston, Hyde Park, Troy / Albany, Catskill, Sleepy Hollow, New York
  • Great Rivers of Florida

    American Cruise Lines
    American Jazz
    Tampa Bay Florida Plant Park 7 Nights Cruise Only from £4811pp Jacksonville, Florida, Palatka, Florida, Lake George, Florida, Green Cove Springs, Florida, Sailing Tolomato River, Florida, St. Augustine, Florida, Amelia Island, Florida, Jacksonville, Florida
  • Mississippi River Gateway

    American Cruise Lines
    American Heritage
    Gateway Arch 10 Nights Cruise Only from £4917pp Complimentary pre-cruise hotel stay! New Orleans (Louisiana, USA), Baton Rouge, Natchez (Mississippi), Vicksburg, Cruising the Mississippi, Memphis (Tennessee), New Madrid (Missouri), Paducah (Kentucky), Cruising the Mississippi, St Louis (Missouri)
  • Florida Gulf Coast & Keys

    American Cruise Lines
    Choice of Ships
    Key West 7 Nights Cruise Only from £5402pp Saint Petersburg, Florida, Fort Myers Beach, Florida, Key West, Florida, Marco Island, Florida, Punta Gorda, Florida, Saint Petersburg, Florida
  • Grand Ohio River (Pittsburgh to St. Louis)

    American Cruise Lines
    Choice of Ships
    Pittsburgh Skyline 14 Nights Cruise Only from £5941pp Pittsburgh, Pennsylvania, Marietta, Ohio, Maysville, Kentucky, Cincinnati, Ohio, Louisville, Kentucky, Henderson, Kentucky, Evansville, Indiana, Paducah, Kentucky, Cape Girardeau, Missouri, Saint Louis, Missouri

About American Cruise Lines