The 9 Best Things to See and Do on a Cruise on the Mississippi River
Written by Blue Water Holidays -Thursday February 5th 2026
Cruising along the legendary Mississippi River is an unforgettable adventure. From the birthplace of jazz in New Orleans to the majestic Gateway Arch in St. Louis, each destination along this iconic waterway offers something incredible to see and do.
Whether you're a history lover, a music enthusiast, or someone who simply wants to soak up the beauty of the river’s banks, a cruise along the Mississippi River has it all. Looking to explore this fascinating corner of America and wondering where to begin? Let's dive into the top things to see and do on a Mississippi River cruise.
What Are the Best Things to See and Do on a Mississippi River Cruise?
There are so many incredible things to see and do while cruising the Mississippi River. From the music of New Orleans to the Civil War history of Vicksburg, each stop is a treasure trove of stories. We’ve lined up the best things to see and do on a Mississippi River cruise to help you plan your perfect journey along this famous waterway.
Explore Memphis: The Birthplace of Rock 'n' Roll
There’s no better place to start your Mississippi River cruise than Memphis. This vibrant city is known as the birthplace of rock 'n' roll, and it’s bursting with music history. From the iconic Graceland to the buzzing Beale Street, Memphis will captivate you with its soul, rhythm, and cultural richness.
If you’re on a Mississippi River cruise from Memphis, the first thing you’ll notice is how easy it is to explore this buzzing city, thanks to its walkable downtown and the number of attractions clustered close to the riverfront.
Highlights of visiting Memphis on a Mississippi River cruise:
- Graceland: Walk through the King of Rock ‘n’ Roll’s home and immerse yourself in the world of Elvis Presley.
- Beale Street: This historic street is home to countless live music venues where you can enjoy the sounds of blues, jazz, and soul.
- National Civil Rights Museum: Located at the Lorraine Motel, it’s an essential stop to understand the pivotal moments of the Civil Rights Movement.
- Sun Studio: Known as the birthplace of rock ‘n’ roll, this is where Elvis, Johnny Cash, and Jerry Lee Lewis all recorded their first hits.
Discover St. Louis: Gateway to the West and Iconic Architecture
St. Louis is another quintessential stop on the Mississippi River, renowned for its mix of history, culture, and striking architecture. Known as the "Gateway to the West," St. Louis is where the American expansion began. The Gateway Arch is the city’s most famous landmark and provides breathtaking views of the river and beyond. St. Louis also boasts rich historical attractions, such as the Missouri History Museum and the St. Louis Art Museum, making it a fantastic place to visit on a Mississippi River Cruise for history and culture enthusiasts.
Highlights of visiting St. Louis on a Mississippi River cruise:
- Gateway Arch: Take a tram ride to the top of this towering monument for stunning views of the city and river.
- Missouri History Museum: Learn about St. Louis’ role in the westward expansion and its cultural heritage.
- Anheuser-Busch Brewery: Take a tour of the brewery that made St. Louis famous for its beer.
Step Back in History at Vicksburg: Civil War Landmarks
Vicksburg holds an essential place in American history, especially for Civil War enthusiasts. Known as “The Gibraltar of the West,” this city played a pivotal role in the Civil War. The Siege of Vicksburg was a crucial moment in the war, and today, the city offers an incredible opportunity to explore this fascinating period of American history. With its charming streets, beautiful old buildings, and deep connection to the Mississippi River, Vicksburg provides a perfect balance of learning and sightseeing. It’s a lovely place to visit on a Mississippi River boat cruise, where you can walk in the footsteps of history while enjoying the peaceful river views.
Highlights of visiting St. Louis on a Mississippi River cruise:
- Vicksburg National Military Park: Explore the battlefield and see the monuments that commemorate the Siege of Vicksburg.
- USS Cairo: A Civil War-era ironclad gunboat that was raised from the Mississippi River and now serves as a museum.
- Crisp Museum: A museum with Native American artefacts and exhibits on the region’s history.
Visit Oak Alley Plantation: Antebellum Elegance in Louisiana
Oak Valley Plantation is another of the best places to visit on a river cruise along the Mississippi. Just a short drive from Baton Rouge, the plantation is one of the most photographed sites in Louisiana, and for good reason. The grand oak trees lining the path leading to the mansion are breathtaking - their moss-draped limbs create a canopy over the driveway, making for an unforgettable entrance. This plantation offers a glimpse into Louisiana’s history, showcasing the opulence of the pre-Civil War South while also touching on the complex and difficult past of plantation life.
Highlights of visiting Oak Alley Plantation on a Mississippi River cruise:
- Oak Alley Plantation House: Tour the restored plantation home and learn about its fascinating history.
- The Alley of Oaks: Stroll under the canopy of towering oak trees that have stood for centuries.
- Mint Juleps on the Lawn: Relax with a traditional Southern drink while taking in the view.
Experience New Orleans: Music, Culture, and Cuisine
New Orleans is the soulful heart of the Mississippi River. Known for its jazz music, rich Creole cuisine, and historical French Quarter, New Orleans is a city like no other. Whether you’re indulging in beignets at Café du Monde or exploring the historic Garden District, New Orleans promises an unforgettable experience.
Highlights of visiting New Orleans on a Mississippi River cruise:
- The French Quarter: Wander through the colourful, historic streets of this iconic neighbourhood, filled with music, food, and culture.
- National WWII Museum: A deeply moving museum dedicated to the history of World War II and its impact on America.
- Jackson Square: A picturesque square surrounded by historic buildings, street musicians, and artists.
- Creole Cuisine: Savour some of the best food in the country, from gumbo to po' boys and beignets.
Cruise the Upper Mississippi: St. Paul to Dubuque
The Upper Mississippi is the part of the river that feels the most untouched, offering a serene journey through charming small towns and magnificent river views. It’s the perfect place to explore on a Mississippi River cruise for those who want to experience the natural beauty of the river, from the majestic bluffs to the lush forests.
Highlights of visiting the Upper Mississippi on a Mississippi River cruise:
- St. Paul: Visit the historic starting point of the Mississippi River and explore this charming city known for its art and history.
- Dubuque: Take a ride on the Fenelon Place Elevator and explore the colourful Victorian mansions.
- La Crosse: Explore this beautiful town surrounded by three rivers and enjoy the views from Grandad Bluff.
- Red Wing: Known for its artistic heritage, Red Wing offers a charming downtown and beautiful views of the river.
Journey on the Ohio and Mississippi Rivers: Historical Highlights
For those who want to experience two of America’s most important rivers, you can also visit the Ohio River on some Mississippi River cruises. The Ohio River played a key role in the development of the American frontier, while the Mississippi River offers a chance to explore the cultural and historical heart of the country. Together, these rivers offer a rich journey through America’s past.
Highlights of visiting the Ohio River on a Mississippi River cruise:
- Pittsburgh: Start your journey in Pittsburgh, a city known for its steel industry and scenic riverfront views.
- Louisville: Visit the home of the Kentucky Derby and enjoy a tour of the famous Jim Beam distillery.
- Cincinnati: Explore this lively city with its rich cultural scene, museums, and theatres.
- St. Louis: End your journey at the Gateway Arch, the tallest monument in the United States, and enjoy the city’s world-class attractions.
Explore Baton Rouge: Louisiana’s Capital and Riverfront
Baton Rouge, the capital of Louisiana, has a rich and diverse history that comes alive during a visit. Known as "The Red Stick," this city offers a unique glimpse into Louisiana’s culture, blending French, African, and Southern influences. Whether you want to wander through history, take in the city’s architecture, or sample some amazing local food, Baton Rouge has plenty to keep you busy. Baton Rouge provides a fascinating blend of old and new, while visiting on a cruise on the Mississippi River, with grand historic buildings alongside modern-day attractions.
Highlights of visiting Baton Rouge on a Mississippi River cruise:
- Louisiana State Capitol: One of the tallest state capitol buildings in the U.S., this imposing structure is an important part of Baton Rouge’s history. It’s where the state’s legislature meets. From the observation deck, you can enjoy panoramic views of the city and the Mississippi River.
- Old State Capitol: Often called the "Castle on the River," this Gothic-style building is now a museum. It offers a glimpse into the past, with exhibits on Louisiana’s political history and beautiful stained-glass windows that are well worth seeing.
- Baton Rouge’s Riverfront: The Mississippi Riverfront in Baton Rouge is a wonderful spot to relax and enjoy the views. It’s home to parks, walking trails, and several museums, including the Louisiana Art and Science Museum, perfect for an afternoon of exploration.
- Swamp Tours: If you're after something a little more adventurous, Baton Rouge offers several swamp tours. These boat trips take you through Louisiana’s wild wetlands, where you can spot alligators, birds, and other wildlife while learning about the local ecosystem.
Discover Natchez: Antebellum Homes and Scenic River Views
Natchez, perched high above the Mississippi River, is one of the most picturesque towns in the South. Known for its well-preserved antebellum architecture, it’s a place where history and Southern hospitality combine. As the oldest city on the Mississippi River, Natchez offers a window into the past, with stately mansions and gardens that showcase the grandeur of the pre-Civil War era.
Highlights of visiting Natchez on a Mississippi River cruise:
- Longwood Plantation: A stunning octagonal mansion that was never completed due to the Civil War, Longwood is an architectural marvel. It’s an example of the grandeur of the era, and touring the home offers insight into the history of the South and the families who lived there.
- Historic Downtown Natchez: The downtown area is full of beautifully preserved buildings from the 18th and 19th centuries.
- Natchez Bluff: The bluff offers some of the best views of the Mississippi River, and it’s a perfect spot to sit and relax after a day of sightseeing.
- Tours of Antebellum Homes: Natchez is known for its antebellum architecture, and you can explore many of the grand homes that still stand today.
Ready for a Cruise on the Mississippi River?
A Mississippi River cruise offers more than just a boat ride - it’s a deep dive into the heart of America. From the lively streets of New Orleans to the peaceful, scenic beauty of the Upper Mississippi, every destination on the river offers its own unique charm and history. Whether you're exploring plantations, Civil War battlefields, or the homes of legendary musicians, there’s something for everyone on a Mississippi River cruise.
Curious about cruising the Mississippi River? Discover our collection of unforgettable cruises on the Mississippi that bring you to the very best of this iconic New Orleans waterway. Reach out to begin planning your perfect getaway.
FAQs
Yes, cruise ships absolutely do go down the Mississippi River! In fact, cruising the Mississippi River is one of the best ways to experience this iconic waterway and the cities that line its banks. However, it's important to note that we're typically talking about river cruises rather than traditional ocean-going cruise ships.
River cruises are specifically designed to navigate inland waterways like the Mississippi, and these ships are usually much smaller than the large ocean liners. The Mississippi is navigable all the way from Minnesota down to Louisiana, and river cruise ships frequently travel these routes, offering scenic views, historical tours, and a relaxed atmosphere. These cruises often feature paddlewheel riverboats and smaller ships, offering a more intimate experience compared to larger ocean liners!
The best time to cruise the Mississippi River is in the spring or fall, when the weather is mild and the landscapes are at their most beautiful. Summer can be hot, but it’s also when the river is busiest with tourists.
Expect a relaxing journey filled with history, culture, and natural beauty. You’ll enjoy guided shore excursions, music performances, and plenty of opportunities to explore small towns, historic sites, and scenic vistas.
Yes! Mississippi River cruises are great for families. There are guided tours, educational opportunities, and plenty of space for relaxation, making it an ideal vacation for all ages.